1. e4 c5
The Sicilian Defense (1. e4 c5) is the most popular and statistically highest-scoring response to 1. e4. Black immediately fights for the center with a flank pawn, creating asymmetric positions that offer winning chances for both sides.
Position after 1. e4 c5
Named after an early analysis from Italy, the Sicilian became a world-class weapon through the games of Bobby Fischer, Garry Kasparov, and Magnus Carlsen. The Najdorf Variation was Fischer's lifelong favorite.